Road closure: Drivers advised to avoid major junction near Leamington and Warwick
The incident is affecting the Sherbourne roundabout on the sections leading to the A46, M40 and the A429.
However, Warwickshire Police hope that the road will reopen before 3pm.
Warwickshire Police said: "Earlier this morning a lorry shed its load and, as a consequence, a road closure has been put in place.
"As of 1.13pm today, May 30, the clean-up operation is expected to last around another 90 minutes."